Saracens will welcome Munster to the Ricoh Arena while defending Champions Cup champions Leinster will once again match up with Toulouse in a replay of their Pool stage encounters.
Once again, Leinster and Munster are back into the final four of the Heineken Champions Cup with Leinster seeing off Ulster in a thriller in the Aviva Stadium while Munster edged out Edinburgh in Murrayfield thanks to a second-half try from Keith Earls.
Meanwhile Saracens obliterated Glasgow as they look to get back to the Champions Cup final after winning the competition in 2017 while Toulouse pipped Racing 92 on Sunday to get another shot at Leinster.
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Leinster number eight Jack Conan said that his side's 21-18 win over Ulster was the toughest game he's played in all year.
A late Ross Byrne penalty was the difference between the two sides in a thriller and Conan was immense for Leinster with 16 carries, 18 tackles and a try assist, while he added that sides that want to win the tournament must be able to grind out results like that victory.
"It was probably the toughest game I've played all year," said Conan in his post-match interview.
"Massive credit to Ulster. They came down here and threw the kitchen sink at us. They were incredible to be fair. I thought we gave them a few easy opportunities with knockdowns and penalties, general ill-discipline, but hats off to them, they put in an incredible shift for 80 minutes.
"It's incredible to be back here in the Aviva with Leinster and having a full house today, it means a lot to the lads. It wasn't pretty today but that's what championship sides do, they win. Even when it's not good and pretty, they grind out a win."
